کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6100555 1211076 2012 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Genotyping should be considered the primary choice for pre-treatment evaluation of thiopurine methyltransferase function
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های گوارشی
پیش نمایش صفحه اول مقاله
Genotyping should be considered the primary choice for pre-treatment evaluation of thiopurine methyltransferase function
چکیده انگلیسی
There is a risk for TPMT misclassification when only genotyping or phenotyping is used, but it is not reasonable to check both in all patients. Since TPMT genotyping is the more reliable test, especially in TPMT heterozygotes, we suggest that genotyping should be considered the primary choice for the pre-treatment evaluation of TPMT function before initiation of thiopurine therapy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Crohn's and Colitis - Volume 6, Issue 6, July 2012, Pages 655-659
نویسندگان
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