کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6113447 | 1590717 | 2016 | 10 صفحه PDF | دانلود رایگان |
- Typical and atypical carcinoids represent 1-5% of all lung malignancies.
- Surgery is the treatment of choice for loco-regional disease.
- Advanced lung carcinoids requires a multidisciplinary approach.
- No recognized standard of care is available for advanced lung carcinoids.
An estimated 20% to 30% of all neuroendocrine tumours originate in the bronchial tree and lungs. According to the 2015 World Health Organization categorization, these tumours are separated into four subtypes characterized by increasing biological aggressiveness: typical carcinoid, atypical carcinoid, large-cell neuroendocrine carcinoma and small-cell carcinoma. Although typical and atypical lung carcinoids account for less than 1-5% of all pulmonary malignancies, the incidence of these neoplasms has risen significantly in recent decades. Surgery is the treatment of choice for loco-regional disease but for advanced lung carcinoids there is no recognized standard of care and successful management requires a multidisciplinary approach. The aim of this review is to provide a useful guide for the clinical management of lung carcinoids.
Journal: Critical Reviews in Oncology/Hematology - Volume 100, April 2016, Pages 167-176