کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6114147 | 1213520 | 2014 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Molecular RHD screening of RhD negative donors can replace standard serological testing for RhD negative donors
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
هماتولوژی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
This work aims to assess the value of a generalized molecular RHD screening strategy which could replace routine serological screening of weak D by indirect antiglobulin test. Three independent studies were performed at the two Blood Transfusion Services Berne and Zurich. Donors investigated were 652 RhD negative, but RhC and/or RhE positive, 17,391 mainly Rhccee, and 8200 with normal RhCcEe phenotype distribution. In study I single samples, in studies II and III minipools of 24 and 20 donor samples were tested, respectively. Among 26,243 phenotypically RhD negative blood donors, 65 carriers of RHD alleles were identified. Thirty-one of them were redefined as RhD positive.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Transfusion and Apheresis Science - Volume 50, Issue 2, April 2014, Pages 163-168
Journal: Transfusion and Apheresis Science - Volume 50, Issue 2, April 2014, Pages 163-168
نویسندگان
Peter Gowland, Christoph Gassner, Hein Hustinx, Martin Stolz, Jochen Gottschalk, Jean-Daniel Tissot, Jutta Thierbach, Andreas Maier, Sonja Sigurdardottir, Franziska Still, Stefano Fontana, Beat M. Frey, Christoph Niederhauser,