Genotype impact on HCV RNA levels determined with the VERSANT HCV RNA 1.0 Assay (kPCR)

The VERSANT HCV RNA 1.0 Assay substantially underestimates HCV RNA concentrations in HCV subtype 2a samples and in HCV subtype 3a and 4a samples containing certain isolates. This may be caused by mismatches with the target sequences due to the primer and/or probe design.