کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6126657 1592772 2015 44 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Plants as antimalarial agents in Sub-Saharan Africa
ترجمه فارسی عنوان
گیاهان به عنوان عوامل ضد مالاریا در کشورهای جنوب صحرای آفریقا
کلمات کلیدی
مالاریا، ضد مالاریا، گیاهان، عوامل شیمیایی، جنوب صحرای آفریقا،
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی انگل شناسی
چکیده انگلیسی
Although the burden of malaria is decreasing, parasite resistance to current antimalarial drugs and resistance to insecticides by vector mosquitoes threaten the prospects of malaria elimination in endemic areas. Corollary, there is a scientific departure to discover new antimalarial agents from nature. Because the two antimalarial drugs quinine and artemisinin were discovered through improved understanding of the indigenous knowledge of plants, bioprospecting Sub-Saharan Africa's enormous plant biodiversity may be a source of new and better drugs to treat malaria. This review analyses the medicinal plants used to manage malaria in Sub-Saharan Africa. Chemical compounds with antiplasmodial activity are described. In the Sub-Saharan African countries cited in this review, hundreds of plants are used as antimalarial remedies. While the number of plant species is not exhaustive, plants used in more than one country probably indicate better antimalarial efficacy and safety. The antiplasmodial data suggest an opportunity for inventing new antimalarial drugs from Sub-Saharan-African flora.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Acta Tropica - Volume 152, December 2015, Pages 32-48
نویسندگان
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