Detection of active schistosome infection by cell-free circulating DNA of Schistosoma japonicum in highly endemic areas in Sorsogon Province, the Philippines

Schematic diagram of diagnostic examinations and treatment of schistosomiasis. Current diagnostics for schistosomiasis are the detection of parasite ova, parasite-specific antibodies, and pathological lesions. All three diagnostics involve ova-related phenomena, and their results do not always reflect active schistosome infection.