Prevalence and risk factors associated to pruritus in Plasmodium vivax patients using chloroquine in the Brazilian Amazon

- Frequency of chloroquine-induced pruritus in vivax malaria in the Amazon is 20%.
- Allergy and high parasitaemia are risk factors for chloroquine-induced pruritus.
- Recurrence of pruritus is extremely common.
- New management strategies need to be investigated.