Diarylheptanoid compounds from Alnus nepalensis express in vitro and in vivo antifilarial activity

- We examine the antifilarial activity of Alnus nepalensis.
- Extract and molecules were assayed in vitro and in vivo systems using the lymphatic filariid Brugia malayi.
- Structure of new molecules was done with the help of spectroscopic analysis.
- Isolated compounds were active on parasite life stages in vitro.
- Diarylheptanoid compounds may provide a lead for design and development of new antifilarial agent(s).