Sulfadoxine-pyrimethamine resistance in Plasmodium falciparum: A zoomed image at the molecular level within a geographic context

► Reviewing the problem of Plasmodium falciparum resistance to sulfadoxine-pyrimethamine. ► Discussing the use of molecular markers in the prediction of sulfadoxine-pyrimethamine resistance. ► Addressing the evolution and spread of these markers in a geographic context.