کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6131196 | 1222217 | 2010 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Epidemiology and clinical features of community-acquired, healthcare-associated and nosocomial bloodstream infections in tertiary-care and community hospitals
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کلمات کلیدی
Extended-spectrum β-lactamases - β-lactamases طیف گسترده ایmethicillin-resistant Staphylococcus aureus - استافیلوکوک اورئوس مقاوم به متیسیلینNosocomial infections - عفونت های بیمارستانیBloodstream infections - عفونت های خونینHealthcare-associated infections - عفونت های مرتبط با سلامتCommunity-acquired infections - عفونتهای دریافتی جامعهMulticentre study - مطالعات چندرسانه ای
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروب شناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Classification of bloodstream infections (BSIs) as community-acquired (CA), healthcare-associated (HCA) and hospital-acquired (HA) has been proposed. The epidemiology and clinical features of BSI according to that classification in tertiary-care (TH) and community (CH) hospitals were investigated in a prospective cohort of 821 BSI episodes from 15 hospitals (ten TH and five CH hospitals) in AndalucÃa, Spain. Eighteen percent were CA, 24% were HCA and 58% were HA. The incidence of CA and HCA BSI was higher in CH than in TH (CA: 3.9 episodes per 1000 admissions vs. 2.2, p <0.01; HCA: 5.0 vs. 2.9, p <0.01), whereas the incidence of HA BSI was lower (7.7 vs. 8.7, p <0.01). In CA and HCA BSI, the respiratory tract was more frequently the source in CH than in TH (CA: 30% vs. 15%; HCA: 20% vs. 9%, p â¤0.03). In HCA BSI, chronic renal insufficiency and tunnelled catheters were less frequent in CH than in TH (11% vs. 26% and 7% vs. 19%, p â¤0.03), although chronic ulcers were more frequent (22% vs. 8%, p 0.008). BSIs as a result of methicillin-resistant Staphylococcus aureus or Pseudomonas aeruginosa were very rare in CA episodes, although extended-spectrum β-lactamase-producing Escherichia coli (ESBLEC) caused a similar proportion of all BSIs in CA, HCA and HA episodes. Multivariate analysis revealed no significant difference in mortality rates in CH and TH. HCA infections should be considered as a separate class of BSI in both TH and CH, although differences between hospitals must be considered. CA BSIs were not caused by multidrug-resistant pathogens, except for ESBLEC.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Microbiology and Infection - Volume 16, Issue 9, September 2010, Pages 1408-1413
Journal: Clinical Microbiology and Infection - Volume 16, Issue 9, September 2010, Pages 1408-1413
نویسندگان
J. RodrÃguez-Baño, M.D. López-Prieto, M.M. Portillo, P. Retamar, C. Natera, E. Nuño, M. Herrero, A. del Arco, A. Muñoz, F. Téllez, M. Torres-Tortosa, A. MartÃn-Aspas, A. Arroyo, A. Ruiz, R. Moya, J.E. Corzo, L. León, J.A. Pérez-López,