کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6131450 | 1593035 | 2016 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Cell biology of Candida albicans-host interactions
ترجمه فارسی عنوان
زیست شناسی سلولی از تعاملات کاندیدا آلبیکنس-میزبان
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موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروب شناسی
چکیده انگلیسی
Candida albicans is a commensal coloniser of most people and a pathogen of the immunocompromised or patients in which barriers that prevent dissemination have been disrupted. Both the commensal and pathogenic states involve regulation and adaptation to the host microenvironment. The pathogenic potential can be downregulated to sustain commensalism or upregulated to damage host tissue and avoid and subvert immune surveillance. In either case it seems as though the cell biology of this fungus has evolved to enable the establishment of different types of relationships with the human host. Here we summarise latest advances in the analysis of mechanisms that enable C. albicans to occupy different body sites whilst avoiding being eliminated by the sentinel activities of the human immune system.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Microbiology - Volume 34, December 2016, Pages 111-118
Journal: Current Opinion in Microbiology - Volume 34, December 2016, Pages 111-118
نویسندگان
Alessandra da Silva Dantas, Kathy K Lee, Ingrida Raziunaite, Katja Schaefer, Jeanette Wagener, Bhawna Yadav, Neil AR Gow,