The role of mitochondria in cytosolic-nuclear iron-sulfur protein biogenesis and in cellular iron regulation

- Mitochondria contain the conserved ABC transporter Atm1 in the inner membrane.
- Atm1 is crucial for cytosolic-nuclear iron-sulfur protein biogenesis.
- Atm1 is involved in the regulation of cellular iron homeostasis.
- Atm1 exports a still unknown, sulfur- and glutathione-containing molecule.