Microtubule-based transport in filamentous fungi

► Dynein-driven and kinesin-driven microtubule-based transport is linked to neuropathology. ► Filamentous fungi are valuable models to study transport by dynein and kinesin. ► The diversity of fungal cargos that use microtubule-based transport is expanding. ► Fungal models provide insight into transport initiation at microtubule terminals. ► Knowledge of transport regulation in fungi informs efforts to understand neurological disease.