Importance of the Candida albicans cell wall during commensalism and infection

► The Candida cell wall contains virulence factors, antigens and PAMPs. ► The cell wall is cortical for the transition between commensalism and virulence. ► The yeast to hypha transition markedly affects wall composition and immune reactivity. ► Cellular morphogenesis is critical for the equilibrium between commensalism and virulence.