The role of Dectin-1 in the host defence against fungal infections

► Dectin-1 is an important innate immune receptor that recognises β-glucans. ► Dectin-1 is involved in immunity to several species of pathogenic fungi. ► Dectin-1 mediates intracellular signalling through Syk/CARD9 and Raf1. ► Dectin-1 is involved in the induction of Th1 and Th17 antifungal responses.