کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6132539 1222520 2009 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Nitrosative and oxidative stress responses in fungal pathogenicity
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروب شناسی
پیش نمایش صفحه اول مقاله
Nitrosative and oxidative stress responses in fungal pathogenicity
چکیده انگلیسی
Fungal pathogenicity has arisen in polyphyletic manner during evolution, yielding fungal pathogens with diverse infection strategies and with differing degrees of evolutionary adaptation to their human host. Not surprisingly, these fungal pathogens display differing degrees of resistance to the reactive oxygen and nitrogen species used by human cells to counteract infection. Furthermore, whilst evolutionarily conserved regulators, such as Hog1, are central to such stress responses in many fungal pathogens, species-specific differences in their roles and regulation abound. In contrast, there is a high degree of commonality in the cellular responses to reactive oxygen and nitrogen species evoked in evolutionarily divergent fungal pathogens.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Microbiology - Volume 12, Issue 4, August 2009, Pages 384-391
نویسندگان
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