The performance of the VIKIA® HIV1/2 rapid test-Evaluation of the reliability and sensitivity

Although several studies have demonstrated that the sensitivity and specificity of rapid HIV tests are comparable to those of enzyme immunoassays, none have addressed the rapidity with which these tests can yield a result and the reliability of such results. In this study, we investigated the performance of VIKIA® HIV1/2 rapid tests regarding early reactive results and the stability of these results after sample addition. The results showed that using HIV-1 or HIV-2 positive samples, a positive result could be observed as early as 1 min after the addition of the sample. The ability of this test to detect early HIV-1 primary infection was also assessed using seroconversion specimens. The results demonstrate the high sensitivity of this test, and its suitability for the identification of seroconversion samples in the context of primary infection with HIV-1.