Stable allele frequency distribution of the polymorphic region of SURFIN4.2 in Plasmodium falciparum isolates from Thailand

► SURFIN4.2 locates on Plasmodium falciparum-infected erythrocyte-surface. ► Positive selection was detected on C-terminal of the extracellular region. ► Temporal changes of allele frequency distribution was assessed using Thai isolates. ► Allele frequency distribution of areas in C-terminal region did not change for 14 years.