کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6137243 | 1593968 | 2012 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Geographic, symptomatic and laboratory predictors of parasitic and bacterial causes of diarrhoea in travellers
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروبیولوژی و بیوتکنولوژی کاربردی
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چکیده انگلیسی
An observational study of patients presenting with diarrhoea to a walk-in service for returning travellers was conducted with the aim of identifying features that would help predict whether pathogens were bacterial or parasitic. In total, 509 cases were included, of which a bacterial aetiology was found in 55/440 (12.5%) and a parasitic cause in 51/428 (11.9%). Patients with symptoms of â¤14 days were significantly more likely to have a bacterial diagnosis than those with longer symptoms (p < 0.001), whereas parasitic causes of diarrhoea were not associated with length of symptoms and became proportionately more likely with time. Raised CRP, faecal white cells and fever were all predictive of positive bacterial culture (p<0.001, p = 0.001 and p = 0.001, respectively) but did not predict parasitic infection. Travellers to South and Southeast Asia were more likely to have parasites detected in their stool than travellers to other tropical areas (OR = 1.96; p = 0.041). Gender, ethnicity, reason for travel and length of stay abroad were not significantly associated with the faecal pathogen identified. These findings should help guide appropriate antimicrobials when empirical therapy is indicated.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene - Volume 106, Issue 9, September 2012, Pages 549-553
Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene - Volume 106, Issue 9, September 2012, Pages 549-553
نویسندگان
Alastair C. McGregor, Christopher J.M. Whitty, Stephen G. Wright,