کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6138210 | 1227006 | 2014 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Malaria, primigravidae, and antibodies: knowledge gained and future perspectives
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
انگل شناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Malaria, primigravidae, and antibodies: knowledge gained and future perspectives Malaria, primigravidae, and antibodies: knowledge gained and future perspectives](/preview/png/6138210.png)
چکیده انگلیسی
Pregnant women have an increased risk of malaria infection, independent of previously acquired immunity. Women in their first pregnancy and children under the age of five are the primary victims of malaria worldwide. Pregnant women develop antibodies against placenta-adhesive parasites in a parity-dependent manner. Various efforts to understand the targets, quality, and quantity of this antibody response could aid the design of an effective vaccine against placental malaria. This review focuses on the research that has led to the current understanding of the antibody response that primigravidae (PG) acquire to Plasmodium falciparum malaria and draws from this knowledge to suggest serology and PG as sentinels for malaria transmission.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Trends in Parasitology - Volume 30, Issue 2, February 2014, Pages 85-94
Journal: Trends in Parasitology - Volume 30, Issue 2, February 2014, Pages 85-94
نویسندگان
Ricardo AtaÃde, Alfredo Mayor, Stephen J. Rogerson,