کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6154520 1246281 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effects of antimicrobial photodynamic therapy and surgical endodontic treatment on the bacterial load reduction and periapical lesion healing. Three years follow up
ترجمه فارسی عنوان
اثرات درمان فتودینامیک ضد میکروبی و درمان اندودنتیکس جراحی بر کاهش بار باکتریال و بهبود زخم پری اپیکال. سه سال پیگیری
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
چکیده انگلیسی


- This paper evaluates the effects of Antimicrobial PDT associated with endodontic surgery on periapical lesions.
- A 3 years follow up was performed to assess the bone healing process.
- Antimicrobial PDT associated with endodontic surgery was able to effectively reduce the initial microbial load.
- There was no indication that PDT treatment promoted any interference in the bone healing process.
- Antimicrobial PDT offers an efficient non-toxic means of destroying microorganisms after using conventional therapy.

SummaryBesides the advances in endodontics, there are situations in which surgery is necessary to retain a tooth that otherwise would be extracted. This study analyzes the microbial reduction after conventional periapical surgery followed by antimicrobial photodynamic therapy (aPDT) in 3 years follows up. Twenty-eight teeth needing periapical surgery were enrolled in this study. Microbiological samples were taken after: (1) accessing the lesion, (2) surgical procedure, and (3) aPDT. The teeth received a full mucoperiosteal flap, osteotomy with a high-speed bur, manual curettage of lesion and of the root, root-end resection and retrograde cavities prepared using ultrasonic retro-tips. After the conventional procedure the cavities received an aqueous solution of methylene blue (60 μM, 3 min) and were irradiated with a diode laser λ = 660 nm (6 min, 15 J). After aPDT, a retrograde filling with mineral trioxide aggregate, flap re-positioning, and sutures conventionally ended the procedure. In all the cases, a periapical X-ray exam was taken before and after the surgical procedure. The microbiological samples showed an overall significant reduction, surgical procedure achieved a mean reduction of about 3.5 log while aPDT achieved a 5 log reduction. After 36 months of follow up the patients had, in average a reduction of 78% of the periapical lesion area. It appears that surgical endodontic treatment associated with antimicrobial photodynamic therapy highly improves the microbial reduction compared to the traditional technique and this could directly affect the treatment prognosis and periapical lesion healing.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Photodiagnosis and Photodynamic Therapy - Volume 12, Issue 4, December 2015, Pages 575-580
نویسندگان
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