کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6190498 1257381 2014 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Towards a simple objective framework for the investigation and treatment of cancer cachexia: The Glasgow Prognostic Score
ترجمه فارسی عنوان
در راستای یک چارچوب عینی ساده برای تحقیق و درمان سرطان سینه: پیشآگهی گلاسکو
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
چکیده انگلیسی

Progress in the treatment of progressive involuntary weight loss in patients with cancer (cancer cachexia) remains dismally slow. Cancer cachexia and its associated clinical symptoms, including weight loss, altered body composition, poor functional status, poor food intake, and poorer quality of life, have long been recognised as indicators of poorer prognosis in the patient with cancer. In order to make some progress a starting point is to have general agreement on what constitutes cancer cachexia. In recent years a plethora of different definitions and consensus statements have been proposed as a framework for investigation and treatment of this debilitating and terminal condition. However, there are significant differences in the criteria used in these and all include poorly defined or subjective criteria and their prognostic value has not been established.The aim of the present review was to examine the hypothesis that a systemic inflammatory response accounts for most of the effect of cancer cachexia and its associated clinical symptoms on poor outcome in patients with cancer. Furthermore, to put forward the case for the Glasgow Prognostic Score to act a simple objective framework for the investigation and treatment of cancer cachexia.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cancer Treatment Reviews - Volume 40, Issue 6, July 2014, Pages 685-691
نویسندگان
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