کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6275865 1614874 2012 17 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The behavioral phenotype of pituitary adenylate-cyclase activating polypeptide-deficient mice in anxiety and depression tests is accompanied by blunted c-Fos expression in the bed nucleus of the stria terminalis, central projecting Edinger-Westphal nucleu
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
The behavioral phenotype of pituitary adenylate-cyclase activating polypeptide-deficient mice in anxiety and depression tests is accompanied by blunted c-Fos expression in the bed nucleus of the stria terminalis, central projecting Edinger-Westphal nucleu
چکیده انگلیسی
▶We examined anxiety levels and c-Fos response to acute stress of PACAP deficient mice. ▶PACAP−/− mice show reduced anxiety in marble burying and light-dark box tests. ▶PACAP−/− mice display brain area-specific reduction in magnitude of c-Fos response. ▶The c-Fos response of mutants is abolished in the DR and blunted in BSTov and EWcp. ▶Limbic, hypothalamic as well as brainstem stress centers are modulated by PACAP.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience - Volume 202, 27 January 2012, Pages 283-299
نویسندگان
, , , , , ,