کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6276211 1614880 2011 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Molecular adaptations of apoptotic pathways and signaling partners in the cerebral cortex of human cocaine addicts and cocaine-treated rats
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
Molecular adaptations of apoptotic pathways and signaling partners in the cerebral cortex of human cocaine addicts and cocaine-treated rats
چکیده انگلیسی
▶Pro-apoptotic Fas-FADD receptor complex is downregulated in brains of cocaine addicts. ▶Pro-apoptotic mitochondrial cytochrome c is reduced in brains of cocaine addicts. ▶Anti-apoptotic t-DARPP, truncated DARPP-32, is reduced in brains of cocaine addicts. ▶Nuclear PARP-1, a sensor of DNA damage, is increased in brains of cocaine addicts. ▶Chronic cocaine in rats only increased t-DARPP content in the cerebral cortex.154
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience - Volume 196, 24 November 2011, Pages 1-15
نویسندگان
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