Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; ABC; ATP-binding cassette; AKT; V-Akt murine thymoma viral oncogene homolog; ALDH1; aldehyde dehydrogenase 1; AR; androgen receptor; Bad; Bcl-2-associated death promoter; Bak; Bcl-2 homologous antagonist killer; Bax; Bcl-2-associated X protein; Bcl-2; B-c
مقالات ISI پیچیدگی سیگنالینگ ناشی از مرگ (ترجمه نشده)
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Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; CNS; central nervous system; C-SNAM; caspase-3 sensitive nanoaggregation MRI probe; CT; computed tomography; DISC; death-inducing signaling complex; DOPE; 1,2-dioleoyl-sn-glycero-3-phosphatidyl ethanolamine; DOTA; 1,4,7,10-tetraazacyclododecane-1,4,7,10-t
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; â¢OH; hydroxyl radical; 2,2-BP; 2,2-bipyridyl; ABC; ATP-binding cassette; AIF; apoptosis-inducing factor; AMPK; AMP-activated protein kinase; AMPKK; AMPK kinase; ANT; adenine nucleotide translocase; AP-1; activator protein 1; Apaf-1; protease activating
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; BSO; Buthionine sulphoximine; DISC; Death-inducing signaling complex; DTNB; 5,5â²-dithiobis-(2-nitrobenzoic acid); DR5; Death receptor 5; FADD; Fas-Associated protein with Death Domain; FLIP; FADD-like IL-1β-converting enzyme-inhibitory protein; NAC; N-
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; aCasp3; activated-caspase 3; Apaf; apoptotic protease-activating factor; BDNF; brain-derived neurotrophic factor; CNS; central nervous system; CREB; cAMP response element-binding protein; CRNs; Cajal-Retzius neurons; DISC; death-inducing signaling compl
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; Lipid rafts; Signal transduction; IGF-I/PI3K/Akt signaling; Fas/CD95; CASMER; Cancer; APL; alkylphospholipid analogue; CASMER; cluster of apoptotic signaling molecule-enriched rafts; DED; death effector domain; DD; death domain; DISC; death-inducing signa
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; AMPK; AMP-activated protein kinase; DISC; death-inducing signaling complex; DMSO; dimethyl sulfoxide; mp; melting point; MTS; 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium); NMR; nuclear magnetic resonance; ppm;
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; SLeA/X; sialyl Lewis antigen A and X; STn; sialyl Tn antigen; PSA; polysialic acid; SAMPs; self-associated molecular patterns; Siglecs; sialic acid-binding immunoglobulin-like lectins; ITIMs; immunoreceptor tyrosine-based inhibitory motifs; NK cell; natur
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; ADAM; (a disintegrin and metalloprotease) metallopeptidase; ALPs; alkyl-lysophospholipids; CD24; signal transducer CD24 (glycosylphosphatidylinositol-anchored receptor); CD44; CD44 antigen (receptor for hyaluronic acid); CXCR4; chemokine receptor type 4;
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; ALP; alkylphospholipid; ASK1; apoptosis signal-regulating kinase 1; CT; CTP:phosphocholine cytidylyltransferase; DISC; death-inducing signaling complex; EGF; epidermal growth factor; ER; endoplasmic reticulum; ERK; extracellular-signal-regulated kinase; J
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; Abl; Abelson leukemia proto-oncogene; ADAP; adhesion and degranulation promoting adapter protein (Fyb, SLAP-130); Asc; apoptosis-associated speck-like protein containing a CARD; BCR; B-cell receptor; C3G; Crk SH3 domain-binding guanine nucleotide exchange
The role of XIAP in resistance to TNF-related apoptosis-inducing ligand (TRAIL) in Leukemia
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; TRAIL; TNF-related apoptosis-inducing ligand; XIAP; X-linked inhibitor of apoptosis protein; cFLIP; cellular FLICE-inhibitory protein; bcl-2; B-cell lymphoma 2; IAP; inhibitor of apoptosis proteins; Mcl-1; myeloid cell leukemia-1; Apo-2L; Apo2 ligand; DR;
S-Nitrosylation of the Death Receptor Fas Promotes Fas Ligand-Mediated Apoptosis in Cancer Cells
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; Colon Cancer; Tumor; Signaling; Localization; ALPS; autoimmune lymphoproliferative syndrome; Cys; cysteine; DISC; death-inducing signaling complex; FADD; Fas-associated death domain; FasL; Fas-ligand; FLICE; FADD-like interleukin-1-beta-converting enzyme;
SOCS-1 ameliorates smoke inhalation-induced acute lung injury through inhibition of ASK-1 activity and DISC formation
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; SOCS-1; suppressor of cytokine signaling-1; ALI; acute lung injury; ARDS; acute respiratory distress syndrome; SAECs; small airway epithelial cells; GFP; green fluorescent protein; SH2; Src homology 2; ASK-1; apoptosis signal-regulating kinase-1; DISC; de
Ca2+ signaling and Src-kinases-controlled cellular functions
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; Ca2+ channels; Cell signaling; Phosphatases; Receptors; Src-family kinases; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxyli
Autophagy in ischemic stroke
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; 3-MA; 3-methyladenine; Aβ; amyloid β; AIF; apoptosis-inducing factor; Akt; protein kinase B; AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; Atg; autophagy-related genes; ATP; adenosine 5â²-triphosphate; BBB; blood-brain ba
Overexpression of FADD and Caspase-8 inhibits proliferation and promotes apoptosis of human glioblastoma cells
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; GBM; glioblastoma; NC; negative control; FADD; fas Associated protein with Death Domain; HRP; horse radish peroxidase; OD; optical density; FCM; flow cytometry; qRT-PCR; quantitative real-time polymerase chain reaction; SD; standard deviation; DR5; death
Tumor suppressor RYBP harbors three nuclear localization signals and its cytoplasm-located mutant exerts more potent anti-cancer activities than corresponding wild type
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; BCOR; BCL6 corepressor; DED; death effector domain; DEDD; DED containing DNA-binding protein; DISC; death-inducing signaling complex; EGFP; enhanced green fluorescence protein; FADD; Fas-associated death domain; FANK1; Fibronectin type III and ankyrin rep
Targeting the Fas/FasL system in Rheumatoid Arthritis therapy: Promising or risky?
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; AP; activator protein; APAF; apoptosis protease activating factor; CAD; caspase-activated DNase; CHO; Chinese hamster ovary; CIA; collagen-induced arthritis; DD; death domain; DED; death effector domain; DISC; death-inducing signaling complex; DR; death r
Functional interaction between hMYH and hTRADD in the TNF-α-mediated survival and death pathways of HeLa cells
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; MutY homolog (MYH); TNFR-associated death domain (TRADD); Tumor necrosis factor alpha (TNF-α); Death-inducing signaling complex; NFκB nuclear translocation
Triclosan induces Fas receptor-dependent apoptosis in mouse neocortical neurons in vitro
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; caspase; cysteine-aspartic acid protease; DISC; death-inducing signaling complex; DMSO; dimethyl sulfoxide; DTT; dithiothreitol; EDTA; ethylenediaminetetraacetic acid; FADD; Fas-associated death domain; FasR; Fas receptor; FBS; fetal bovine serum; GAPDH;
Key role of phosphodiesterase 4A (PDE4A) in autophagy triggered by yessotoxin
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; AKAP; A-kinase anchoring proteins; Bcl-2; B-cell lymphoma 2 anti-apoptotic protein; BSA; bovine serum albumin; C and R; catalytic and regulatory regions; cAMP; adenosine 3â²,5â²-cyclic monophosphate; Cav-1; caveolin-1; CREB; cAMP response element bindin
Protein tyrosine phosphatase 1B (PTP1B): A key regulator and therapeutic target in liver diseases
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; PTKs; protein tyrosine kinases; PTPs; protein tyrosine phosphatases; PTP1B; protein tyrosine phosphatase 1B; NAFLD; non-alcoholic fatty liver disease; HCC; hepatocellular carcinoma; DSPs; dual specificity phosphatases; LMW; low molecular weight; RPTPs; tr
Protective effect of linarin against d-galactosamine and lipopolysaccharide-induced fulminant hepatic failure
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; ALT; alanine aminotransferase; AST; aspartate aminotransferase; DISC; death-inducing signaling complex; FADD; Fas-associated death domain; GalN; d-galactosamine; H&E; hematoxylin and eosin; IFN; interferon; IL; interleukin; IRAK; interleukin-1 receptor-as
Histone deacetylase inhibitor (HDACI) mechanisms of action: Emerging insights
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; HDAC inhibitor; DNA damage response; DNA repair; Cell cycle checkpoints; Apoptosis; Rational combinations; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; APAF-1; apoptotic protease activating factor 1; ASK1; apoptosis signal-regulating ki
Neuroprotection of S-nitrosoglutathione against ischemic injury by down-regulating Fas S-nitrosylation and downstream signaling
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; 7-NI; 7-nitroindazole; DD; death domain; DED; death effector domain; DISC; death-inducing signaling complex; DTT; dithiothreitol; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol tetraacetic acid; FADD; Fas-associated death domain; GSNO; S-nit
PSAP induces a unique Apaf-1 and Smac-dependent mitochondrial apoptotic pathway independent of Bcl-2 family proteins
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; PSAP; presenilin-associated protein; PARP; poly(ADP-ribose) polymerase; Bcl-2; B-cell lymphoma 2; LacZ; β-galactosidase; Z-VAD-fmk; benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone; FADD; Fas-associated death domain; DISC; death-inducing signaling comple
Aldose reductase inhibition enhances TRAIL-induced human colon cancer cell apoptosis through AKT/FOXO3a-dependent upregulation of death receptors
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; AOM; azoxymethane; AR; aldose reductase; ARIs; AR inhibitors; CRC; colorectal cancer; DISC; death-inducing signaling complex; DR; death receptor; TNF; tumor necrosis factor; PARP; poly(ADP-ribose) polymerase; TRAIL; tumor necrosis factor-related apoptosis
AXL Mediates TRAIL Resistance in Esophageal Adenocarcinoma
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; EAC; esophageal adenocarcinoma; TRAIL; tumor necrosis factor-related apoptosis-inducing ligand; FLIP; FLICE-inhibitory protein; DISC; death-inducing signaling complex; FADD; Fas-associated death domain protein;
Small molecule inhibitors of the HPV16-E6 interaction with caspase 8
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; HPV; human papillomavirus; TNF R1; tumor necrosis factor receptor 1; FADD; fas-associated protein with death domain; TRAIL; TNF-related apoptosis-inducing ligand protein; TRADD; tumor necrosis factor receptor type 1-associated death domain protein; TRAF;
Research reportNeuroprotection of co-activation of GABA receptors by preventing caspase-3 denitrosylation in KA-induced seizures
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; KA; kainic acid; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionate; GABA; γ-Aminobutyric acid; FasL; Fas-ligand; FADD; Fas-associated death domain; DISC; death-inducing signaling complex; Trx; thioredoxin; TrxR; Trx reductase; SNO; S-nitrosothiol;
Enriching the human apoptosis pathway by predicting the structures of protein-protein complexes
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; AIF; apoptosis-inducing factor, mitochondrion-associated, 1; Apaf-1; apoptotic peptidase activating factor 1; Bax; BCL2-associated X protein; Bcl-2; B-cell lymphoma 2; Bcl-XL; Bcl-extra large; Bid; BH3 interacting domain death agonist; CASP3; caspase-3; C
Programmed cell death in C. elegans, mammals and plants
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; PCD; programmed cell death; TUNEL; terminal deoxynucleotidyl transferase mediated dUTP nick-end labeling; CARD; caspase recruitment domain; DED; death effector domain; DISC; death-inducing signaling complex; Bcl-2; B-cell-lymphoma; OMM; outer mitochondria
Glutathione and modulation of cell apoptosis
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; âΨ; mitochondrial membrane potential; ANT; adenine nucleotide translocase; Apaf-1; apoptotic protease-activating factor-1; ASK-1; apoptosis signal-regulating kinase-1; ATO; arsenic trioxide; AVD; apoptotic volume decrease; BSO; l-buthionine (S,R)-sulfo
The molecular mechanism of apoptosis upon caspase-8 activation: Quantitative experimental validation of a mathematical model
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; ARK5; AMPK-related protein kinase 5; Bid; BH3-interacting domain death agonist; CARP; caspases-8- and -10-associated RING protein; CASP; caspase; CHX; cycloheximide; DED; death effector domain; DISC; death-inducing signaling complex; EGFP; enhanced green
ORAI-mediated calcium influx in T cell proliferation, apoptosis and tolerance
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; AICD; activation induced cell death; AIRE; autoimmune regulator; APC; antigen-presenting cell; [Ca2+]i; intracellular Ca2+ concentration; CRAC channel; Ca2+ release-activated Ca2+ channel; CREB; cyclic-AMP-responsive element-binding protein; GALT; gut-ass
Caveolin-1 mediates Fas-BID signaling in hyperoxia-induced apoptosis
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; Cav-1; caveolin-1; FADD; Fas-associated death domain protein; NAC; N-acetylcysteine; DISC; death-inducing signaling complex; 2-Br; 2-bromopalmitic acid; CS; catalase; GPX2; glutathione peroxidase 2; Hyperoxia; Fas; Caveolin-1; Apoptosis; Free radicals;
Molecular adaptations of apoptotic pathways and signaling partners in the cerebral cortex of human cocaine addicts and cocaine-treated rats
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; cocaine addiction; postmortem human brain; rat brain; Fas-FADD complex; PARP-1 cleavage; apoptotic signaling; AIF; apoptosis-inducing factor; Akt/PKB; v-akt murine thymoma viral oncogene homologue/protein kinase B; Bax; Bcl-2 associated X protein; Bcl-2
Haplophytin-A induces caspase-8-mediated apoptosis via the formation of death-inducing signaling complex in human promyelocytic leukemia HL-60 cells
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; Haplophytin-A; Apoptosis; Caspases 8; Death-inducing signaling complex
c-Cbl acts as a mediator of Src-induced activation of the PI3K-Akt signal transduction pathway during TRAIL treatment
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; c-Cbl; Casitas B-lineage lymphoma; DD; death domain; DISC; death-inducing signaling complex; DMEM; Dulbecco's modified Eagle's medium; DR4; TRAIL-R1; DR5; TRAIL-R2; DTT; dithiothreitol; EGF; epidermal growth factor; EGFR; EGF receptor; EGTA; ethylene glyc
Differential regulation of caspase-9 by ionizing radiation- and UV-induced apoptotic pathways in thymic cells
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; Apaf-1; apoptosis protease-activating factor; Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma extra long; Bid; BH3 interacting domain death agonist; BSA; bovine serum albumin; CBB; Coomassie brilliant blue; DAPI; 4â²,6-Diamidino-2-phenylindole; DISC; d
Salicylate-induced degeneration of cochlea spiral ganglion neurons-apoptosis signaling
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; aspirin; tumor necrosis factor; organotypic culture; PCR-array; caspase; NF-κB; AC; auditory cortex; BME; basal medium Eagle; CAD; caspase-activated DNase; CAP; compound action potential; Ct; cycle threshold; DISC; death-inducing signaling complex; FADD;
Lipid raft connection between extrinsic and intrinsic apoptotic pathways
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; APAF-1; apoptotic protease-activating factor-1; CASMER; clusters of apoptotic signaling molecule-enriched rafts; CTx; cholera toxin; DiOC6(3); 3,3â²-dihexyloxacarbocyanine iodide; DR4; death receptor 4; DR5; death receptor 5; DISC; death-inducing signali
CD95 Ligand Is a Proliferative and Antiapoptotic Signal in Quiescent Hepatic Stellate Cells
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; BrdU; bromodeoxyuridine; CD95L; CD95 ligand; CHX; cycloheximide; DISC; death-inducing signaling complex; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; Erk; extracellular signal-regulated kinase; HSC; hepatic stellate cell; JNK; c
Dying a Thousand Deaths: Redundant Pathways From Different Organelles to Apoptosis and Necrosis
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; Akt; proto-oncogene product of the viral oncogene v-akt; AIF; apoptosis inducing factor; Apaf-1; apoptotic protease activating factor-1; ATF6; activating transcription factor 6; Bad; heterodimeric partner for Bcl-xL and Bcl-2; Bak; Bcl2 homologous antagon
17-Allylamino-17-demethoxygeldanamycin overcomes TRAIL resistance in colon cancer cell lines
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; hsp90; 90Â kDa heat-shock protein; 17-AAG; 17-allylamino-17-demethoxygeldanamycin; TRAIL; tumor necrosis factor-related apoptosis-inducing ligand; DR4 and DR5; death receptors 4 and 5, respectively; CI; combination index; DISC; death-inducing signaling co
Hepatic mitochondrial glutathione: transport and role in disease and toxicity
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; ALD; alcohol-induced liver disease; APAP; N-acetyl-p-aminophenol; ASMase; acidic sphingomyelinase; CYP2E1; cytochrome P450 2E1; DISC; death-inducing signaling complex; ER; endoplasmic reticulum; GSH; reduced glutathione; GSSG; oxidized glutathione; HMGCoA
Anesthesia induces neuronal cell death in the developing rat brain via the intrinsic and extrinsic apoptotic pathways
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; immature brain; synaptogenesis; apoptosis; caspase; bcl-2; cytochrome c; AD; anterodorsal thalamic nucleus; AM; anteromedial thalamic nucleus; AV; anteroventral thalamic nucleus; cCBF; cortico-cerebral blood flow; DAB; 3,3â²-diaminobenzidine; DISC; death
Death receptor-mediated apoptosis in human malignant glioma cells: Modulation by the CD40/CD40L system
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; BHK; baby hamster kidney; CD40L; CD40 ligand; CD95L; CD95 ligand; CHX; cycloheximide; DEVD-amc; Asp-Glu-Val-Asp-7-amino-4-methylcoumarin; DISC; death-inducing signaling complex; DMEM; Dulbecco's Modified Eagle's Medium; DR4/5; death receptor 4/5; ECL; enh
Pancreatic Cancer: Basic and Clinical Aspects
Keywords: پیچیدگی سیگنالینگ ناشی از مرگ; CK; cytokeratin; COX; cyclooxygenase; DISC; death-inducing signaling complex; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; FDR; fixed dose rate; 5-FU; 5-fluorouracil; GemOx; gemcitabine and oxaliplatin; MMP; matrix metalloproteina