Keywords: AAV; adeno-associated viruses; ADA; adenosine deaminase deficiency; APCs; antigen presenting cells; AuNC; gold nanoclusters; AuNPs; gold nanoparticles; AuNRs; gold nanorods; BBB; blood-brain barrier; Bcl-2; B-cell lymphoma 2; Cas; CRISPR-associated; ChNPs
مقالات ISI (ترجمه نشده)
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Keywords: 3-HK; 3-hydroxykynurenine; 3-NP; 3-nitropropionic acid; 6âOHDA; 6-hydroxidopamine; AADC; aromatic amino acid decarboxylase; ACA; anterior cerebral artery; ADP; adenosine-5â²-diphosphate; ALDH; aldehyde dehydrogenases; ALS; amyotrophic lateral sclerosis
Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4- isoxazole propionic acid; ASI; Axon-spine interface; Ca2+; calcium; CNS; Central nervous system; CS-EP; Corticostriatal-evoked potential; DBS; deep brain stimulation; DA; Dopamine; DARPP-32; dopamine-regulated neuronal
Keywords: AC; adenylate cyclase; ADHD; attention deficit hyperactivity disorder; ACC; anterior cingulate cortex; ALS; amyotrophic lateral sclerosis; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ATP; adenosine triphosphate; BBB; blood-brain barrier;
Keywords: D2R; dopamine receptor; cAMP; cyclic adenosine monophosphate; PKA; protein kinase A; DARPP-32; dopamine and cAMP-regulated phosphoprotein; PP1; protein phosphatase 1; MEK; mitogen-activated protein kinase/ERK kinase; ERK; extracellular-signal regulated ki
Keywords: STZ; Streptozotocin; HFD; High-fat diet; CPP; Conditioned place preference; RD; Regular diet; NAc; Nucleus accumbens; ICV; intra-cerebroventricular; VTA; Ventral tegmental area; DAT; Dopamine transporter; DARPP-32; dopamine- and cAMP-regulated neuronal ph
Keywords: Cannabinoid receptor; Huntington's disease; Social behavior; RotaRod test; DARPP-32;
Keywords: AMPK; AMP-activated protein kinase; CamKKβ; calmodulin-dependent kinase kinase β (CamKKβ); DARPP-32; dopamine-and cAMP-regulated phosphoprotein of Mr 32 kDa; ERK; extracellular signal-regulated kinase; HDACs; histone deacetylases; MAO-A; monoamine oxi
Keywords: ANOVA; analysis of variance; AUC; area under the curve; BP; breaking point; DARPP-32; dopamine and cAMP-regulated phosphoprotein of Mr 32,000; FR; fixed-ratio; NAcS; nucleus accumbens shell; PR; progressive ratio; SDS; sodium dodecyl sulfate; Thr; threoni
Keywords: Aging; Dopamine; DARPP-32; DAT; Implicit and Explicit Memory; Sequence Learning; Serial Reaction Time Task;
Prenatal vitamin D deficiency does not exacerbate behavioural impairments associated with prenatal ethanol exposure in juvenile male mice
Keywords: Juvenile mouse behaviour; Foetal alcohol exposure; Vitamin D deficiency; 25(OH)D; 25-hydroxyvitamin D (calcidiol); Aadc; aromatic L-amino acid decarboxylase; ADHD; attention deficit hyperactivity disorder; ASD; Autism spectrum disorder; COMT; comethyl tra
Aripiprazole relieves motivational anhedonia in rats
Keywords: Depression; Dopamine; DARPP-32; Nucleus accumbens shell;
Circadian control of p75 neurotrophin receptor leads to alternate activation of Nrf2 and c-Rel to reset energy metabolism in astrocytes via brain-derived neurotrophic factor
Keywords: AQP4; aquaporin 4; BDNF; brain-derived neurotrophic factor; CK2; casein kinase 2; Cry; cryptochrome; CREB; cAMP-response elements binding protein; DARPP-32; dopamine- and cAMP-regulated phosphoprotein of 32 kDa; FoxO1; forkhead box protein O1; Gbe1; glyco
Toll-like receptor-4 regulates anxiety-like behavior and DARPP-32 phosphorylation
Keywords: TLR4; Anxiety; Emotion; mGluRs; DARPP-32;
Pharmacogenetic modulation of STEP improves motor and cognitive function in a mouse model of Huntington's disease
Keywords: Cognitive function; DARPP-32; Hippocampus; Motor coordination; Mutant huntingtin aggregates; phosphoERK1/2; Striatum;
Memantine ameliorates depressive-like behaviors by regulating hippocampal cell proliferation and neuroprotection in olfactory bulbectomized mice
Keywords: Apoptosis; Cell proliferation; Depression; Emotional behavior; Olfactory bulbectomy; Neuroinflammation; ANOVA; analysis of variance; Bax; Bcl-2-associated protein X; Bcl-2; B cell lymphoma/leukemia gene 2; BDNF; brain-derived neurotrophic factor; BrdU; 5-
Activation of NPY-Y2 receptors ameliorates disease pathology in the R6/2 mouse and PC12 cell models of Huntington's disease
Keywords: Aβ; beta-amyloid; ABC; avidin-biotin complex; BBB; blood brain barrier; BDNF; brain derived neurotrophic factor; BSA; bovine serum albumin; CREB; cAMP response element binding protein; cDNA; complementary deoxyribonucleic acid; DAB, 3; 3-diaminobenzidine
The central serotonin2B receptor as a new pharmacological target for the treatment of dopamine-related neuropsychiatric disorders: Rationale and current status of research
Keywords: 5-HT; serotonin; 5-HT2BR; 5-HT2B receptor; AC; adenylate cyclase; APDs; antipsychotic drugs; cAMP; cyclic adenosine monophosphate; CNS; central nervous system; DA; dopamine; DAG; diacylglycerol; DARPP-32; DA and c-AMP-regulated phosphoproteins Mr 32Â kDa;
Molecular basis for the regulation of the circadian clock kinases CK1δ and CK1ε
Keywords: ATP; adenosine triphosphate; CK1; casein kinase 1; CK2; casein kinase 2; CTD; C-terminal domain; TTFL; transcriptional and translational feedback loop; GSK-3β; glycogen synthase kinase 3β; MEFs; mouse embryonic fibroblast cells; ConA; concanavalin A; LP
Fasting biases μ-opioid receptors toward β-arrestin2-dependent signaling in the accumbens shell
Keywords: ANOVA; analysis of variance; CPu; caudate-putamen; DARPP-32; dopamine and cAMP-regulated phosphoprotein of Mr 32,000; FD; food-deprived; GPCRs; G protein-coupled receptors; MOR; μ-opioid receptor; NAcC; nucleus accumbens core; NAcS; nucleus accumbens she
Intrastriatal injection of ionomycin profoundly changes motor response to l-DOPA and its underlying molecular mechanisms
Keywords: AIMs; abnormal involuntary movement scale; ANOVA; analysis of variance; CPU; striatum; CREB; cAMP response element-binding protein; DARPP32; dopamine- and c-AMP-regulated phosphoprotein of 32Â kDa; DREAM; calcium-binding protein downstream regulatory elem
t-Darpp stimulates protein kinase A activity by forming a complex with its RI regulatory subunit
Keywords: CFP; cerulean fluorescent protein; CICF; corrected integrated cell fluorescence; CREB; cAMP response element binding protein; CRE; cAMP response element; Darpp-32; dopamine- and AMP-regulated phosphoprotein of 32Â kDa; DAPI; 4â²,6-diamidino-2-phenylindol
Synaptopathic mechanisms of neurodegeneration and dementia: Insights from Huntington's disease
Keywords: 5-HT; 5-hydroxytryptamine; 7,8-DHF; 7,8-dihydroxyflavone; ACh; acetylcholine; AD; adenosine; ADL; activities of daily living; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMPK; 5â²AMP-activated protein kinase; BDNF; brain-derived neurotro
High vitamin A intake during pregnancy modifies dopaminergic reward system and decreases preference for sucrose in Wistar rat offspring
Keywords: Comt; Catechol-O-methyl transferase; CpG; Cytosine-phosphate-guanine; Darpp-32; DA- and cyclic AMP-regulated phosphoprotein; Dat; Dopamine transporter; Drd1; Dopamine receptor 1; Drd2; Dopamine receptor 2; Drd5; Dopamine receptor 5; HA; AIN-93G diet with
Genetic deletion of Rhes or pharmacological blockade of mTORC1 prevent striato-nigral neurons activation in levodopa-induced dyskinesia
Keywords: AIMs; abnormal involuntary movements; DA; dopamine; DARPP-32; dopamine and cAMP-regulated phosphoprotein, Mr 32Â kDa; D1R; D1 receptor; D2R; D2 receptor; ERK; extracellular-regulated kinase; L-DOPA; levodopa; LID; levodopa-induced dyskinesia; MSNs; medium
Protection by dietary restriction in the YAC128 mouse model of Huntington's disease: Relation to genes regulating histone acetylation and HTT
Keywords: CBP; Creb binding protein; DR; dietary restriction; HD; Huntington's disease; HTT; mutant huntingtin protein; IGF-1; insulin-like growth factor; Ppp1r1b; DARPP-32; SAHA; suberoylanilide hydroxamic acid; WT; wild-type; Huntington's disease; Dietary restric
Acute drug-induced spine changes in the nucleus accumbens are dependent on β-adducin
Keywords: Striatum; Dendritic spines; Dopamine; Dopamine D2 receptors; Caffeine; Antipsychotics; DARPP-32; Phosphorylation;
FoxP1 marks medium spiny neurons from precursors to maturity and is required for their differentiation
Keywords: DARPP-32; dopamine and cyclic adenosine 3â², 5â²- monophosphate-regulated phosphoprotein, 32Â kDa; FoxP1; Forkhead box protein P1; HD; Huntington's disease; MSN; medium spiny projection neuron; FoxP1; DARPP-32; Medium spiny neurons; Neural transplantati
Human t-DARPP is induced during striatal development
Keywords: aa; aminoacids; HD; Huntington's disease; hPSC; human pluripotent stem cell; MSNs; medium spiny neurons; p.c.w.; post conception weeks; pcd; post-conception days; pmd; post-mortem delay; WGE; whole ganglionic eminence; DARPP-32; striatum; medium spiny n
Recombinant Adeno Associated Viral (AAV) vector type 9 delivery of Ex1-Q138-mutant huntingtin in the rat striatum as a short-time model for in vivo studies in drug discovery
Keywords: HD; Huntington's disease; mHTT; mutant Huntingtin; rAAV; recombinant Adeno Associated Virus; LV; lentivirus; tNAA; total N-Acetyl Aspartate; Myo-Ins; myoinositol; GFP; green fluorescent protein; NeuN; neuronal nuclei; DARPP-32; dopamine- and cyclic AMP-re
Anti-semaphorin 4D immunotherapy ameliorates neuropathology and some cognitive impairment in the YAC128 mouse model of Huntington disease
Keywords: CNS; central nervous system; DARPP-32; dopamine- and cAMP-regulated phosphoprotein; EAE; experimental autoimmune encephalomyelitis; HTT; huntingtin; HD; Huntington disease; ICV; intracerebroventricular; IP; intraperitoneal; IT; intrathecal; mAb; monoclona
Impramine, fluoxetine and clozapine differently affected reactivity to positive and negative stimuli in a model of motivational anhedonia in rats
Keywords: ANOVA; analysis of variance; BP; breaking point; DARPP-32; dopamine and cAMP-regulated phosphoprotein of Mr 32,000; FR; fixed-ratio; NAcS; nucleus accumbens shell; PR; progressive ratio; SA; self-administration; SDS; sodium dodecyl sulfate; Thr; threonine
Elevated postmortem striatal t-DARPP expression in schizophrenia and associations with DRD2/ANKK1 polymorphism
Keywords: ANCOVA; analysis of covariance; ANKK1; ankyrin-repeat containing kinase 1; CaN; calcineurin; DARPP-32; dopamine- and cAMP-regulated phosphoprotein of molecular weight 32Â kDa; DIBS; Diagnostic Instrument for Brain Science; DLPFC; dorsolateral prefrontal c
Haloperidol-induced Nur77 expression in striatopallidal neurons is under the control of protein phosphatase 1 regulation by DARPP-32
Keywords: Striatum; Dopamine; Orphan nuclear receptors; Antipsychotics; A2AR; adenosine 2A receptor; CDK5; cyclin-dependent kinase 5; DAPI; 4â²,6â²-Diamidino-2-phenylindole; DARPP-32; dopamine- and cAMP-regulated phosphoprotein of 32Â kDa; D1R, D2R, and D3R; dopa
Negative cerebral blood volume fMRI response coupled with Ca2Â +-dependent brain activity in a dopaminergic road map of nociception
Keywords: MEMRI; Mn2Â +-enhanced MRI; pCREB; phosphorylated cAMP response-element-binding; SN; substantia nigra; CBV; cerebral blood volume; T1WIs; T1-weighted images; FLASH; fast/low-angle shot; TR; repetition time; TE; echo time; FA; flip angle; FOV; field of vie
Adenosine A1 receptor stimulation reduces D1 receptor-mediated GABAergic transmission from striato-nigral terminals and attenuates l-DOPA-induced dyskinesia in dopamine-denervated mice
Keywords: ACSF; artificial cerebrospinal fluid; cAMP; cyclic adenosine monophosphate; DA; dopamine; DARPP-32; DA- and cAMP regulated phosphoprotein of 32Â kDa; D1R; D1 receptor; A1R; A1 receptor; eIPSCs; evoked IPSCs; sIPSCs; spontaneous IPSCs; IEI; inter-event int
MicroRNA-132 dysregulation in Toxoplasma gondii infection has implications for dopamine signaling pathway
Keywords: 3-MT; 3-methoxytyramine; 5-HT; serotonin; 5-HIAA; 5-hydroxyindoleacetic acid; BDNF; brain derived neurotrophic factor; COMT; catechol-O-methyltransferase; DOPAC; 3,4-dihydroxyphenylacetic acid; DRD1; dopamine receptor D1; DRD5; dopamine receptor D5; DARPP
Normalizing dopamine D2 receptor-mediated responses in D2 null mutant mice by virus-mediated receptor restoration: Comparing D2L and D2S
Keywords: AAV; adeno-associated virus; BSA; bovine serum albumin; D2L; D2 receptor long form; D2S; receptor short form; DARPP-32; Dopamine- and cyclic AMP-regulated phosphoprotein of about 32 kD; Drd2â/â; D2 receptor null mutant; Drd2ex6â/ex6â; D2L receptor
Cocaine represses protein phosphatase-1Cβ through DNA methylation and Methyl-CpG Binding Protein-2 recruitment in adult rat brain
Keywords: Cocaine; Drugs of abuse; DNA methylation; Epigenetics; Protein phosphatase-1; MeCP2; Rett syndrome; CGI; CpG Island; ChIP; chromatin immunoprecipitation; CPP; conditioned place preference; CPu; caudate putamen; CREB; cAMP response element-binding protein;
Decreased CaMKII and PKC activities in specific brain regions are associated with cognitive impairment in neonatal ventral hippocampus-lesioned rats
Keywords: ANOVA; analysis of variance; ASR; acoustic startle response; CaMKII; Ca2+/calmodulin-dependent protein kinase II; cAMP; cyclic AMP; DA; dopamine; DARPP-32; dopamine- and cAMP-regulated phosphoprotein-32; EDTA; ethylenediaminetetraacetic acid; EGTA; ethyle
Dopamine modulates attentional control of auditory perception: DARPP-32 (PPP1R1B) genotype effects on behavior and cortical evoked potentials
Keywords: Attention; Selective attention; Conflict monitoring; Auditory processing; Dopamine; Evoked potentials; DARPP-32; PPP1R1B;
Increased ratio of calcineurin immunoreactive neurons in the caudate nucleus of patients with schizophrenia
Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate; BA46; Brodmann's Area 46; BDNF; brain neurotrophic factor; CaN; Calcineurin; DAB; diaminobenzidine; DG; dentate gyrus; DARPP-32; dopamine- and cAMP-regulated phosphoprotein of molecular weight 32,00
Cell type-specific localization of optineurin in the striatal neurons of mice: implications for neuronal vulnerability in Huntington's disease
Keywords: Huntington's disease; optineurin; huntingtin; striatum; interneurons; neurodegeneration; ChAT; choline acetyltransferase; CR; calretinin; DARPP-32; dopamine and cAMP-regulated phosphoprotein of 32 kDa; HD; Huntington's disease; Htt; huntingtin; MSNs; medi
Modulation of methamphetamine-induced nitric oxide production by neuropeptide Y in the murine striatum
Keywords: aCSF; artificial cerebrospinal fluid; DARPP-32; dopamine and cyclic adenosine 3â²,5â²-monophosphate-regulated phosphoprotein, 32Â kDa; ICR; Institute for Cancer Research; ip; intraperitoneal; METH; (+)-methamphetamine hydrochloride; NPY; neuropeptide Y;
Long-term daily access to alcohol alters dopamine-related synthesis and signaling proteins in the rat striatum
Keywords: AC; adenyl cyclase; AR; aldose reductase; cGMP; cyclic guanylyl monophosphate; CREB; cyclic adenosine monophosphate (cAMP) responsive element binding protein; DA; dopamine; DARPP-32; DA and cAMP regulated phosphoprotein; DHAP; converting dihydroxyacetone
The NMDA receptor subunit GluN3A protects against 3-nitroproprionic-induced striatal lesions via inhibition of calpain activation
Keywords: NMDAR; N-methyl-d-aspartate receptor; 3-NP; 3-nitropropionic acid; DARPP-32; dopamine and c-AMP-regulated phosphoprotein, 32; GFP; green fluorescent protein; MSN; medium spiny neurons; STEP; striatal-enriched protein tyrosine phosphatase; CAMKII; Ca2Â +/C
7-Nitroindazole down-regulates dopamine/DARPP-32 signaling in neostriatal neurons in a rat model of Parkinson's disease
Keywords: 6-OHDA; Dorsolateral; Neostriatum; SNpc; TH; nNOS; DARPP-32; 7-NI; EBSTPD, Parkinson's disease; NOS, nitric oxide synthase; 7-NI, 7-Nitroindazole; DA, dopamine; NO, Nitric Oxide; 6-OHDA, 6-Hydroxydopamine; TH, Tyrosin Hydroxylase; CPu, Caudate–Putamen com
Muscarinic receptors acting at pre- and post-synaptic sites differentially regulate dopamine/DARPP-32 signaling in striatonigral and striatopallidal neurons
Keywords: Muscarinic receptor; M5 receptor; Dopamine; DARPP-32; Phosphorylation; Striatum
Variation of the gene coding for DARPP-32 (PPP1R1B) and brain connectivity during associative emotional learning
Keywords: BMS; Bayesian Model Selection; BMA; Bayesian Model Averaging; BVAQ; Bermond-Vorst Alexithymia Questionnaire; DCM; Dynamic Causal Model; GLM; General Linear Model; IFG; Inferior frontal gyrus; MFG; Medial frontal gyrus; RFX; Random effects analysis; VOI;
The novel adenosine A2A antagonist prodrug MSX-4 is effective in animal models related to motivational and motor functions
Keywords: Depression; Effort-related choice behavior; Parkinson's disease; Drug-induced parkinsonism; Locomotion; Tremulous jaw movements; c-Fos; DARPP-32;