کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6276623 1614901 2011 14 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Possible involvement of syntaxin 1A downregulation in the late phase of allodynia induced by peripheral nerve injury
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
Possible involvement of syntaxin 1A downregulation in the late phase of allodynia induced by peripheral nerve injury
چکیده انگلیسی
▶Syntaxin (STX) 1A is a membrane protein controlling synaptic exocytosis. ▶Peripheral nerve injury increased the frequency of mEPSCs in the spinal dorsal horn. ▶Peripheral nerve injury gradually decreased STX 1A expression in the dorsal horn. ▶STX 1A knockdown by an antisense ODN led to the gradual development of allodynia. ▶STX 1A might be involved in nerve injury-induced spinal nociceptive plasticity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience - Volume 175, 17 February 2011, Pages 344-357
نویسندگان
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