کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6282418 1615140 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Urinary BDNF-to-creatinine ratio is associated with aerobic fitness
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
Urinary BDNF-to-creatinine ratio is associated with aerobic fitness
چکیده انگلیسی
Circulating levels of brain-derived neurotrophic factor (BDNF) are known to be affected by aerobic exercise. As the previous research focus in humans has been to examine peripheral BDNF levels through blood, serum, and platelet assay, the present study investigated the association between basal urinary BDNF concentration and indices of aerobic fitness in a sample of young adults (n = 52). Aerobic fitness was evaluated with self-report of exercise habits and heart rate (HR) assessment during a sub-maximal Step Test. BDNF concentration was determined by enzyme-linked immunosorbent assay and adjusted for creatinine. Results indicated that the basal BDNFlog/creatinine ratio was positively associated with greater frequency of exercise and, during aerobic challenge, a quicker rise in HR upon exercise, lower peak HR during exercise, and lower HR during the recovery period, each indicative of enhanced fitness. These results highlight the utility of urine capture as a non-invasive technique to assess for exercise-mediated changes in peripheral BDNF.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Letters - Volume 559, 24 January 2014, Pages 169-173
نویسندگان
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