کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6283 476 2013 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mesoporous silica-encapsulated gold nanoparticles as artificial enzymes for self-activated cascade catalysis
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Mesoporous silica-encapsulated gold nanoparticles as artificial enzymes for self-activated cascade catalysis
چکیده انگلیسی

A significant challenge in chemistry is to create synthetic structures that mimic the complexity and function of natural systems. Here, a self-activated, enzyme-mimetic catalytic cascade has been realized by utilizing expanded mesoporous silica-encapsulated gold nanoparticles (EMSN-AuNPs) as both glucose oxidase- and peroxidase-like artificial enzymes. Specifically, EMSN helps the formation of a high degree of very small and well-dispersed AuNPs, which exhibit an extraordinarily stability and dual enzyme-like activities. Inspired by these unique and attractive properties, we further piece them together into a self-organized artificial cascade reaction, which is usually completed by the oxidase-peroxidase coupled enzyme system. Our finding may pave the way to use matrix as the structural component for the design and development of biomimetic catalysts and to apply enzyme mimics for realizing higher functions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomaterials - Volume 34, Issue 11, April 2013, Pages 2600–2610
نویسندگان
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