Effects of olanzapine and clozapine on memory acquisition, consolidation and retrieval in mice using the elevated plus maze test

► Olanzapine and clozapine impaired the acquisition of spatial memory. ► Clozapine disturbed consolidation of spatial memory, while olanzapine had no effect. ► Clozapine and olanzapine disrupted the retention of spatial memory. ► Olanzapine may be a superior treatment for schizophrenia compared to clozapine.