کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6285720 | 1615177 | 2008 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Complex network analysis of human ECoG data
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
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چکیده انگلیسی
Localization of the epileptogenic zone (EZ) is an important issue in epileptology, even though there is not a unique definition of the epileptic focus. By using complex network analysis of electrocorticographic (ECoG) data we identify three singular areas in the temporal lobe of epileptic patients, the node with highest local synchronization power, the most connected node, and the node with highest interactions load. Connectivity in the data is extracted from the Minimum Spanning Tree (MST) of global correlations. We address the question whether removal of these nodes during the surgery is crucial in the suppression or reduction in the quantity of post-operative seizures. From five ECoG records, local areas with high synchronization power appear to be significantly involved in the development of epileptic seizures. The other two areas seem not to be fundamental in the seizures onset and development. Moreover, the approach proposed shed new light in cortical connectivity patterns in the human temporal lobe. All the analyzed records are during the inter-ictal state.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Letters - Volume 447, Issues 2â3, 12 December 2008, Pages 129-133
Journal: Neuroscience Letters - Volume 447, Issues 2â3, 12 December 2008, Pages 129-133
نویسندگان
Guillermo J. Ortega, Rafael G. Sola, Jesús Pastor,