کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6291769 1302500 2011 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Zygocotyle lunata: Proteomic analysis of the adult stage
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی انگل شناسی
پیش نمایش صفحه اول مقاله
Zygocotyle lunata: Proteomic analysis of the adult stage
چکیده انگلیسی

The somatic extract of Zygocotyle lunata (Trematoda: Paramphistomidae) adults collected from experimentally infected mice was investigated using a proteomic approach to separate and identify tryptic peptides from the somatic extract of Z. lunata adult worms. A shot-gun liquid chromatography/tandem mass spectrometry procedure was used. We used the MASCOT search engine (Matrix-Science) and ProteinPilot software v2.0 (Applied Biosystems) for the database search. A total of 36 proteins were accurately identified from the worms. The largest protein family consisted of metabolic enzymes. Structural, motor and receptor binding proteins and proteins related to oxygen transport were identified in the somatic extract of Z. lunata. This is the first study that attempts to identify the proteome of Z. lunata. However, more work is needed to improve our knowledge of trematodiasis in general and more specifically to have a better understanding about host-parasite relationships in infections with paramphistomes.

Research highlights►The somatic extract of Zygocotyle lunata (Trematoda: Paramphistomidae) adults collected from experimentally infected mice was investigated. ► The largest protein family consisted of metabolic enzymes. ► Structural, motor and receptor binding proteins and proteins related to oxygen transport were identified in the somatic extract of Z. lunata.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Experimental Parasitology - Volume 128, Issue 2, June 2011, Pages 133-137
نویسندگان
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