کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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6308212 | 1618851 | 2015 | 7 صفحه PDF | دانلود رایگان |
- Non-specific symptoms among residents exposed to emissions from wastes were studied.
- Unlike previous studies, individual-specific chemical exposures were used.
- Exposures play an important role in the genesis of non-specific symptoms.
- The effects of low-to-moderate exposures seem to be mediated by odor annoyance.
Adverse health effects of exposure to high levels of air pollutants from biodegradable wastes have been well-studied. However, few investigations have examined the potential effects of chronic exposure to low-to-moderate levels on non-specific health symptoms among residents. Besides, most studies have relied on distances to waste sites to assign exposure status, and have not investigated whether the exposure-symptoms associations are direct or mediated by odor annoyance. In this study, individual-level exposures to a proxy indicator of biodegradable waste pollution (ammonia, NH3) in non-urban residences (n = 454) during 2005-2010 were characterized by data from emission-dispersion validated models. Logistic regression and mediating analyses were used to examine associations between exposures and questionnaire-based data on annoyance and non-specific symptoms, after adjusting by person-specific covariates. Strong dose-response associations were found between exposures and annoyance, and between annoyance and symptoms. Associations between exposures and symptoms (nausea, headache, dizziness, difficulty concentrating and unnatural fatigue) were indirect (annoyance-mediated). This study indicates that environmental exposures play an important role in the genesis of non-specific symptoms among residents exposed to low-to-moderate air pollution from biodegradable wastes, although the effects seem to be indirect, relayed through stress-related mechanisms.
Journal: Chemosphere - Volume 120, February 2015, Pages 371-377