کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6309327 | 1645519 | 2014 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The effects of prenatal exposure to low-level cadmium, lead and selenium on birth outcomes
ترجمه فارسی عنوان
اثرات مواجهه قبل از زایمان با کادمیوم پایین، سرب و سلنیم در نتیجه تولد
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کلمات کلیدی
فلزات، خون مادری، خون بند ناف، ادرار وزن تولد،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
شیمی زیست محیطی
چکیده انگلیسی
To evaluate the current maternal and fetal exposure to cadmium (Cd), lead (Pb) and selenium (Se), and their potential effect on newborn birth outcomes, a cross-sectional study involving an assessment of the levels of these three metals in maternal blood, urine and umbilical cord blood was conducted in 209 pregnant women living in Eastern China. The maternal blood, urine and cord blood samples were collected and measured with inductively coupled plasma mass spectrometry (ICP-MS). The maternal blood concentrations of Cd, Pb and Se (the geometric means (GMs) were 0.48, 39.50 and 143.53 μg Lâ1) were significantly higher than and correlated with those in the cord blood (GM: 0.09, 31.62 and 124.61 μg Lâ1). In the urine samples, the GMs for Cd, Pb and Se were 0.13, 0.48, and 4.78 μg Lâ1, respectively. Passive smoking was found to positively correlate with urine Cd (r = 0.16) and negatively correlate with urine Se (r = â0.29). The maternal blood Se level was negatively associated with the cord Cd levels (r = â0.41). The blood Cd concentration in the mother could significantly affect the newborn birth weight (r = â0.22), but it was not correlated with birth height. We identified cord Se as a new factor which significantly correlated with birth weight. In conclusion, maternal Cd, Pb, Se exposure correlated with their umbilical cord concentration, and maternal Cd exposure might affect the newborn birth weight. Increasing the Se intake might reduce the cord blood Cd concentration and promote the fetal growth.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chemosphere - Volume 108, August 2014, Pages 33-39
Journal: Chemosphere - Volume 108, August 2014, Pages 33-39
نویسندگان
Hong Sun, Wen Chen, Dongyue Wang, Yinlong Jin, Xiaodong Chen, Yan Xu,