Toxicity of silver nanoparticles to rainbow trout: A toxicogenomic approach

► The toxicity of dissolved silver and silver nanoparticles was examined in rainbow trout. ► The bioavailability of hepatic silver was higher for dissolved silver than nanosilver. ► The toxicity of silver differed between dissolved and nanoparticles of silver. ► Nanosilver produced inflammation while silver disturbed the redox status and protein stability in the liver.