کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6315730 | 1619161 | 2016 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Positive associations of serum perfluoroalkyl substances with uric acid and hyperuricemia in children from Taiwan
ترجمه فارسی عنوان
پیوندهای مثبت مواد پرفروفیالکلی سرم با اسید اوریک و هیپوریکمی در کودکان تایوان
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کلمات کلیدی
PFHxAPFHpAperfluorododecanoic acidPerfluorotetradecanoic acidPerfluoroheptanoic acidPolyfluoroalkyl substancesPFDoAPFDAPFNAperfluorohexane sulfonateGBCaPFBSPFHxSIQRPFOAPFOSPerfluorobutane sulfonateORSPFASs95%CI - 95٪ CIperfluorodecanoic acid - اسید perfluorodecanoicPerfluorononanoic acid - اسید PerfluorononanoicUric acid - اسید اوریکPerfluorooctane sulfonate - سولفونات Perfluorooctane95% confidence intervals - فاصله اطمینان 95٪interquartile range - محدوده بین محدبPerfluoroalkyl substances - مواد Perfluoroalkylodds ratio - نسبت شانس هاHyperuricemia - هیپریریسمیChildren - کودکان
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
شیمی زیست محیطی
چکیده انگلیسی
To investigate the risk of hyperuricemia in relation to Perfluoroalkyl substances (PFASs) in children from Taiwan, 225 Taiwanese children aged 12-15 years were recruited from 2009 to 2010. Linear and logistic regression models were employed to examine the influence of PFASs on serum uric acid levels. Findings revealed that eight of ten PFASs analyses were detected in >94% of the participants' serum samples. Multivariate linear regression models revealed that perfluorooctanic acid (PFOA) was positively associated with serum uric acid levels (β = 0.1463, p < 0.05). Of all the PFASs analyses, only PFOA showed a significant effect on elevated levels of hyperuricemia (aOR = 2.16, 95%CI: 1.29-3.61). When stratified by gender, the association between serum PFOA and uric acid levels was only evident among boys (aOR = 2.76, 95%CI: 1.37-5.56). In conclusion, PFOA was found to be associated with elevated serum levels of uric acid in Taiwanese children, especially boys. Further research is needed to elucidate these links.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Environmental Pollution - Volume 212, May 2016, Pages 519-524
Journal: Environmental Pollution - Volume 212, May 2016, Pages 519-524
نویسندگان
Xiao-Di Qin, Zhengmin Qian, Michael G. Vaughn, Jin Huang, Patrick Ward, Xiao-Wen Zeng, Yang Zhou, Yu Zhu, Ping Yuan, Meng Li, Zhipeng Bai, Gunther Paul, Yuan-Tao Hao, Wen Chen, Pau-Chung Chen, Guang-Hui Dong, Yungling Leo Lee,