کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6329324 | 1619777 | 2014 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Stereoisomeric profiling of drugs of abuse and pharmaceuticals in wastewaters of Valencia (Spain)
ترجمه فارسی عنوان
نمایه سازی استریو ایزومریل داروهای سوء استفاده و دارو در فاضلاب والنسیا (اسپانیا)
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کلمات کلیدی
داروها، مواد مخدر، استریایزومرها، انانتیومرها، فاضلاب، داروهای کریل،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
شیمی زیست محیطی
چکیده انگلیسی
The enantiomeric and diastereomeric profiling of chiral pharmaceuticals (ephedrine, norephedrine, atenolol and venlafaxine) and illicit drugs (amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxy-N-methylamphetamine (MDMA) and 3,4-methylenedioxy-N-ethylamphetamine (MDEA)) was undertaken over a period of fourteen consecutive days in three wastewater treatment plants (WWTPs) in the city of Valencia, Spain. Degradation efficiency of WWTPs was found to be compound and enantiomer dependent. Selective enantiomer enrichment was observed for several target analytes. Amphetamine and MDMA were enriched with R(â)-enantiomers. 1S,2S(+)-pseudoephedrine was found to be more readily degradable during activated sludge treatment than its diastereomer 1R,2S(â)-ephedrine. Atenolol underwent enrichment with either S(â)- or R(+)-enantiomer in different WWTPs. This unexpected enantiomeric variation in the stereoselective degradation of atenolol could be attributed to different processes utilized during activated sludge treatment. The application of (enantiomeric) profiling of wastewater revealed usage patterns of chiral drugs in the Valencia region.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Science of The Total Environment - Volumes 494â495, 1 October 2014, Pages 49-57
Journal: Science of The Total Environment - Volumes 494â495, 1 October 2014, Pages 49-57
نویسندگان
Pablo Vazquez-Roig, Barbara Kasprzyk-Hordern, Cristina Blasco, Yolanda Picó,