کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6332013 | 1619799 | 2013 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Organohalogenated contaminants (OHCs) in human serum of mothers and children from Pakistan with urban and rural residential settings
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
شیمی زیست محیطی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
This study aimed to provide first data on the concentrations of different classes of organohalogenated contaminants (OHCs) in human serum from Pakistan, an area with limited information on environmental pollution. Serum samples (N = 85) were collected from mothers (N = 34; age ranged 23-51 years), their children (N = 34; age 3-10 years) and general group (N = 17; age 13-65 years) with rural and urban residential settings. The concentrations of studied OHCs in serum decreased as follows: organochlorinated pesticides (OCPs) > polychlorinated biphenyls (PCBs) > polybrominated diphenyl ethers (PBDEs). Novel brominated flame retardants (NBFRs) were not detected, except for 1,2-bis(2,4,6-tribromophenoxy)-ethane (BTBPE) < 0.2-8 ng/g lipid weight (lw). Low levels of HO-PCBs (< 0.2-20 ng/g lw) were detected, while HO-PBDEs were < 0.2 ng/g lw. âPCBs (2-105 ng/g lw) together with âPBDEs (0.2-6.7 ng/g lw) contributed ~ 5% of the total OHCs body burden. The concentration(s) of major contributors (> 80%) of OCPs ranged from < 1-3645 ng/g lw for 1,1â²-bis-(4-chlorophenyl)-2,2-dichloroethene (p,pâ²-DDE), < 1-445 ng/g lw for β-hexachlorocyclohexane (β-HCH) and from 5 to 200 ng/g lw for pentachlorophenol (PCP). p,pâ²-DDE, the major OHC, was significantly higher (p < 0.05) in rural children than in all other groups. In serum of rural children, the major OHCs were significantly higher (p < 0.05) than the mothers. The current study indicates continuous exposure to humans with already regulated OHCs and highlights the need for further monitoring of these OHCs in the region.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Science of The Total Environment - Volumes 461â462, 1 September 2013, Pages 655-662
Journal: Science of The Total Environment - Volumes 461â462, 1 September 2013, Pages 655-662
نویسندگان
Nadeem Ali, Syed Ali Musstjab Akber Shah Eqani, Riffat Naseem Malik, Hugo Neels, Adrian Covaci,