Effects of in vivo chronic exposure to pendimethalin/Prowl 400® on sanitary status and the immune system in rainbow trout (Oncorhynchus mykiss)

► A bioconcentration of pendimethalin was found in fish flesh affecting the sanitary status. ► Specific and nonspecific immune systems were disturbed after chronic exposure to pendimethalin. ► After a recovery period, fleshes were depurated while immunity parameters did not return to basal levels. ► The commercial product was more immunotoxic than pendimethalin alone.