Selective hydrolysis of α-lactalbumin by Acid Protease A offers potential for β-lactoglobulin purification in whey proteins

► Whey protein hydrolysis under acid pH. ► Selective hydrolysis of α-La. ► Resistance of β-Lg genetic-variant dependent. ► SDS-PAGE and RP-HPLC used to monitor protein hydrolysis. ► Method offers potential for industrial purification of β-Lg.