کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6463207 1361935 2017 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Gastric foveolar dysplasia: a survey of reporting habits and diagnostic criteria
ترجمه فارسی عنوان
دیسپلازی فوئولار معده: بررسی عادات گزارش و معیارهای تشخیصی
کلمات کلیدی
دیسپلازی معده؛ دیسپلازی فوئولار؛ آتیپی واکنش پذیر؛ دیسپلازی آدنوماتوس
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی قانونی
چکیده انگلیسی

SummaryThis study aimed to ascertain views, incidence of reporting and diagnostic criteria for gastric foveolar dysplasia.A questionnaire, a post-questionnaire discussion and microscopic assessment of selected cases was conducted by gastrointestinal pathologists to explore the above-stated aims.Fifty-four percent of respondents never or rarely diagnosed gastric foveolar-type dysplasia. The general consensus was that round nuclei, lack of nuclear stratification, presence of inflammation/damage and surface maturation favoured reactive change; while architectural abnormalities/complexity and nuclear enlargement mainly were used to separate low-grade from high-grade foveolar dysplasia. Immunohistochemistry was rarely used to make the diagnosis of dysplasia and was thought not to be of help in routine practice.Inter-observer agreement in grading of dysplasia versus reactive, and the type of dysplasia (foveolar versus adenomatous), was substantial/almost perfect amongst 35.7% and 21.4% of participants, respectively. This reflects low reproducibility in making these diagnoses.In conclusion, foveolar dysplasia was a rarely made diagnosis among 14 gastrointestinal pathologists, there are no uniform criteria for diagnosis and there is poor inter-observer agreement in separating low-grade foveolar dysplasia from reactive gastric mucosa and low-grade adenomatous dysplasia. Greater awareness and agreed criteria will prevent misdiagnosis of low-grade foveolar dysplasia as reactive, and vice versa.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pathology - Volume 49, Issue 4, June 2017, Pages 391-396
نویسندگان
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