Graphite oxide as support for the immobilization of Ru-BINAP: Application in the enantioselective hydrogenation of methylacetoacetate

► Graphite oxide was functionalized using organosilane or isocyanate as linkers. ► Immobilization of Ru-BINAP onto functionalized-graphite oxide has been achieved. ► Hydrogenation of MAA with hybrid catalysts gave satisfactory enantioselectivities. ► Laminar structure should be preserved for good accessibility to the active sites.