Nanoscrystalline CuO: Synthesis and application as an efficient catalyst for the preparation of 1,2,3-triazole acyclic nucleosides via 1,3-dipolar cycloaddition

► CuO nanowire catalyst prepared with diameter range of 2.5-3.7 nm ► Synthesized at room temperature from metallic cupper powder ► Catalyst for 1,3-dipolar cycloaddition of organic azides to terminal alkynes ► Regioselective synthesis of 1,4-disubstituted in good to excellent yields ► Catalyst found to be reusable and allows one-pot [3 + 2] cycloaddition