dsDNA, ssDNA, G-quadruplex DNA, and nucleosomal DNA electrochemical screening using canthin-6-one alkaloid-modified electrodes

- Canthin-6-one natural β-carboline alkaloid is used as electrode modifier.
- Screening of different DNA forms is obtained with no need of DNA labeling.
- Specific voltammetric signals for different DNA tertiary structures are obtained.
- Different degrees of DNA methylation and the presence of nucleosomal DNA can be discriminated.