Preparation, characterization and use of poly(4-vinylpyridinium) hydrogen sulfate salt as an eco-benign, efficient and reusable solid acid catalyst for the chemoselective 1,1-diacetate protection and deprotection of aldehydes

Poly(4-vinylpyridinium) hydrogen sulfate solid acid was found to be efficient catalyst for preparation of 1,1-diacetate at room temperature and neat condition. Deprotection of the resulting 1,1-diacetates was achieved using the same catalyst in methanol solvent. This new method consistently has the advantage of excellent yields and short reaction times. Further, the catalyst can be reused and recovered for several times but they will be less active.

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► Introducing the new catalyst (as solid acid) for organic transformations.
► Introducing an efficient new method for protection of aldehydes.
► Generality of the method, high yields and very short reaction times.
► Application of solvent-free conditions in the reaction.