کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6660331 | 1426222 | 2015 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Solution thermodynamics of pyrazinamide, isoniazid, and p-aminobenzoic acid in buffers and octanol
ترجمه فارسی عنوان
ترمودینامیک محلول پریازینامید، ایزونیزید و اسید پ-آمینوبنزوئیک در بافر ها و اکتانول
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
مهندسی شیمی (عمومی)
چکیده انگلیسی
The solubility values of pyrazinamide, isoniazid, and p-aminobenzoic acid in buffers (ÑÐ 2.0 and 7.4) and octanol were measured in the temperature range of 293.15 to 313.15Â K. The dissolution Gibbs energy, enthalpy, and entropy were calculated. The dissolving process was endothermic and enthalpy-determined. The activity coefficients of the compounds at infinite dilution were determined based on the solubility data and thermophysical parameters. A positive deviation from the ideality was observed in all the solutions. A common tendency of the solubility increase with a decrease in the activity coefficients at TÂ =Â 298.15Â K was revealed for the investigated solute-solvent systems. The excess thermodynamic solubility functions were calculated from the temperature dependences of the activity coefficients. The solvation processes were found to have a considerable influence on the solubility of the substances in solutions studied.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Chemical Thermodynamics - Volume 91, December 2015, Pages 396-403
Journal: The Journal of Chemical Thermodynamics - Volume 91, December 2015, Pages 396-403
نویسندگان
Svetlana V. Blokhina, Marina V. Ol'khovich, Angelica V. Sharapova, Tatyana V. Volkova, German L. Perlovich,