کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6661757 | 1426557 | 2018 | 34 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Electroanalytical application of molecular imprinted polyaniline matrix for dapsone determination in real pharmaceutical samples
ترجمه فارسی عنوان
استفاده الکتروآنالیز از ماتریس پلی یانین مشتق شده مولکولی برای تعیین داپسون در نمونه های دارویی واقعی
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
مهندسی شیمی (عمومی)
چکیده انگلیسی
An electrochemical sensor based on molecularly imprinted polymer was fabricated for the determination of dapsone (DDS) which represents an antileprotic drug used in animals for the prevention and treatment of diseases. Iron oxide nanoparticles (Fe3O4) as magnetic material was first deposited and followed by the electropolymerization of aniline monomer with and without a template molecule (DDS) at the surface of platinum electrode (Pt). The performance of modified surfaces based on the nanocomposite matrix was investigated using cyclic voltammetry and electrochemical impedance spectroscopy techniques while their configuration was characterized using scanning electronic microscopy images, UV-Visible and Fourier transform infrared spectroscopy. The prepared sensor showed very high recognition ability and selectivity for dapsone. The experimental results showed best analytical performances for DDS detection with an adequate sensitivity of 0.272â¯Î©/mol.â¯Lâ1, a reasonable linear range from 1.0â¯Ãâ¯10â7 to 1.0â¯Ãâ¯10â5 M and a low detection limit of 1.25â¯Ãâ¯10â5 M was obtained. In addition, the developed bioanalytical system was successfully applied for dapsone determination in real samples with high recovery and selectivity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Electroanalytical Chemistry - Volume 818, 1 June 2018, Pages 131-139
Journal: Journal of Electroanalytical Chemistry - Volume 818, 1 June 2018, Pages 131-139
نویسندگان
Houda Essousi, Houcine Barhoumi,