Voltammetric method optimized by multi-response assays for the simultaneous measurements of uric acid and acetaminophen in urine in the presence of surfactant using MWCNT paste electrode

► The synergic effect of carbon nanotubes and cationic surfactant was demonstrated. ► Multi-response and overall desirability shows to be very useful for simultaneous optimization. ► Anti-fouling properties of sensor was observed. ► Uric acid and acetaminophen were successfully determined in urine samples.