Rapid, efficient and selective reduction of aromatic nitro compounds with sodium borohydride and Raney nickel

A new efficient, mild and practical method for reduction of aromatic nitro compounds employing NaBH4/Raney nickel system is reported. The method is simple, inexpensive, easily scaled-up and applicable for large scale preparation of different substituted anilines as well as other heterocyclic aryl amines.

A new efficient, mild and practical method for reduction of aromatic nitro compounds employing NaBH4/Raney nickel system is reported. The method is simple, easily scaled-up and applicable for large scale preparation of different substituted anilines as well as other heterocyclic aryl amines.Figure optionsDownload as PowerPoint slide