One-pot green procedure for Biginelli reaction catalyzed by novel task-specific room-temperature ionic liquids

Cheap and reusable task-specific ionic liquids that bear an alkanesulfonic acid group in an acyclic trialkylammonium cation were found to be effective catalysts for synthesizing 3,4-dihydropyrimidine-2-(1H)-ones via the one-pot three-component Biginelli reaction. The satisfactory results were obtained with good yields, short reaction time and simplicity in the experimental procedure. The catalysts could be recycled and reused six times without noticeably decrease in the catalytic activity.

Cheap and reusable task-specific ionic liquids were found to be effective catalysts for assembling 3,4-dihydropyrimidine-2-(1H)-ones via one-pot three-component Biginelli reaction. Figure optionsDownload as PowerPoint slide